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Single cell RNA sequencing of placenta in patients with gestational diabetes during term pregnancy

GSE267340 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2025/04/16 Platform GPL24676
Summary
We performed the single cell RNAsequencing in the placental tissues of term pregnancies with gestational diabetes mellitus complicated with macrosomia after cesarean section to explore the transcriptome differences and potential mechanisms of placenta in the process of macrosomia in patients with gestational diabetes. Our research helps to understand placental overgrowth in GDMM and its impact on fetal development, providing new insights into the pathogenesis of GDMM and predicting potential therapeutic interventions.
Published in
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia
Zheng S, Feng W, Sun Z et al. · Scientific reports 2025 · PMID 40394177 · doi:10.1038/s41598-025-02490-1
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Also filed as BioProject PRJNA1111104 and SRA study SRP507389. Searching any of these in the dataset finder brings you back here.

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