Transcriptomic effects of PFBA and PFHxA exposure on RPMI2650 cells
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Three-Dimensional Cultured Human Nasal Epithelial Cell Model for Testing Respiratory Toxicity and Neurotoxicity of Air PollutantsEnvironmental science & technology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267705_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1112434 and SRA study SRP508211. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8273317 Transcriptomic status of RPMI2650 cells 1/4
- GSM8273318 Transcriptomic status of RPMI2650 cells 2/4
- GSM8273319 Transcriptomic status of RPMI2650 cells 3/4
- GSM8273320 Transcriptomic status of RPMI2650 cells 4/4
- GSM8273321 Transcriptomic effects of PFBA exposure on RPMI2650 cells 1/4
- GSM8273322 Transcriptomic effects of PFBA exposure on RPMI2650 cells 2/4
- GSM8273323 Transcriptomic effects of PFBA exposure on RPMI2650 cells 3/4
- GSM8273324 Transcriptomic effects of PFBA exposure on RPMI2650 cells 4/4
- GSM8273325 Transcriptomic effects of PFHxA exposure on RPMI2650 cells 1/4
- GSM8273326 Transcriptomic effects of PFHxA exposure on RPMI2650 cells 2/4
- GSM8273327 Transcriptomic effects of PFHxA exposure on RPMI2650 cells 3/4
- GSM8273328 Transcriptomic effects of PFHxA exposure on RPMI2650 cells 4/4
- GSE236956 Effects of PFOA, PFBA, PFHxA, PFOS, PFBS, PFHxS on gene expression in monolayer and non-neuroectoderm cells differentiated from H1 42 samples shares pfba, pfhxa
- GSE292944 Culture Media Strongly Influences Primary Human Bronchial Epithelial Cells' Transcriptomic Response to Ozone Exposure 24 samples shares exposure
- GSE335628 Effects of norepinephrine(NE) and dexamethasone(DEX) exposure on signaling pathways in ciliary body cells 14 samples shares exposure
- GSE294574 Transcriptomic profiling of irradiated HEK293T and NHLF cells to assess cell-type specific responses to γ-ray exposure 12 samples shares exposure
- GSE275227 Transcriptomic changes in Human Umbilical Vein Endothelial Cells (HUVEC) after exposure to Tumor Necrosis Factor-Alpha(TNF-a), AdipoRon, and Sphingosine Kinase Inhibitor (SKI-I) 12 samples shares exposure
- GSE271637 Impacts of Glut1 Deficiency and High Glucose Exposure on Transcriptomic Profiling in Human Brain Microvascular Endothelial Cells 12 samples shares exposure
- GSE330022 Multidimensional Exposure Architecture Shapes Vaping-Associated Transcriptomic Dysregulation in Oral Epithelium 83 samples shares exposure
- GSE336386 Effects of norepinephrine(NE) and dexamethasone(DEX) exposure on signaling pathways in immortalized primary human trabecular meshwork cells. 9 samples shares exposure
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.