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AP-1 regulates heterogeneous cellular dormancy in TNBC

GSE267757 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2024/05/18 Platform GPL11154
Summary
Slow-cycling cells (SCCs) are a heterogeneous subpopulation of tumor cells. They pre-exist in tumor tissues and evade killing by chemotherapeutics that target mitosis due to their dormant nature. We here utilized varieties of fluorescent dyes or proteins (Claret, H2BeGFP, and Violet) retaining method to label and isolate SCCs, and RNA-seq was performed to understand the gene expression characteristics of subpopulations of SCCs.
Published in
CEBPB-high dormant tumor cells drive immune evasion via S100A8 orchestrated tumor-associated macrophages reprogramming
Bai J, Su H, Wang S et al. · Theranostics 2026 · PMID 41799200 · doi:10.7150/thno.124789
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Also filed as BioProject PRJNA1112801 and SRA study SRP508344. Searching any of these in the dataset finder brings you back here.

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