The potential global neutralizing effects of AB-free kava against cigarette smoke exposure in mice
RNA-seq (gene expression) · mouse · 29 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 29 samples: 20 distinct titles, 4 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Flavokavains A- and B-Free Kava Enhances Resilience against the Adverse Health Effects of Tobacco Smoke in MiceACS pharmacology & translational science · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE267842_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1113353 and SRA study SRP508580. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 29 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8279460 NC-2
- GSM8279461 NC-3
- GSM8279462 NC-4
- GSM8279463 Kava-1
- GSM8279464 Kava-2
- GSM8279465 Kava-3
- GSM8279466 Kava-4
- GSM8279467 CS-2
- GSM8279468 CS-3
- GSM8279469 CS-4
- GSM8279470 Kava+CS-2
- GSM8279471 Kava+CS-3
- GSM8279472 Kava+CS-4
- GSM8279473 M_1_2_1_6
- GSM8279474 M_1_2_2_6
- GSM8279475 M_1_2_3_6
- GSM8279476 M_1_2_4_6
- GSM8279477 M_2_2_1_6
- GSM8279478 M_2_2_2_6
- GSM8279479 M_2_2_4_6
- GSM8279480 M_2_2_5_6
- GSM8279481 M_3_1_1_6
- GSM8279482 M_3_1_2_6
- GSM8279483 M_3_2_1_6
- GSM8279484 M_3_2_2_6
- GSM8279485 M_4_2_2_6
- GSM8279486 M_4_2_3_6
- GSM8279487 M_4_2_4_6
- GSM8279488 M_4_2_5_6
- GSE331129 Transcriptome profiling of colorectal tissues from AOM-induced colorectal cancer mice with cigarette smoke exposure 18 samples shares cigarette, exposure, smoke
- GSE283495 Intestinal epithelial cell diversity and function in respect to age, anatomical localization, and microbial exposure - the global transcriptome 29 samples shares exposure, global
- GSE303772 Ontogenically distinct alveolar macrophages mediate cigarette smoke-induced inflammation and damage [RNA-Seq] 24 samples shares cigarette, smoke
- GSE303713 Ontogenically distinct alveolar macrophages mediate cigarette smoke-induced inflammation and damage 14 samples shares cigarette, smoke
- GSE249957 RNA sequencing analyses reveal the potential anti-inflammatory mechanisms of acacetin against ODG/R injuries in microglia 12 samples shares potential, against
- GSE272849 EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling 119 samples shares potential, global
- GSE272549 EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling [ChIP-Seq] 40 samples shares potential, global
- GSE272545 EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling [ATAC-Seq] 30 samples shares potential, global
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.