GEO series
Transcription of HIV-1 at sites of intact latent provirus integration [scRNA-seq]
GSE267988
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2024/06/25
GPL24676
Summary
The study examined proviral and neighboring gene transcription at sites of intact latent HIV-1 integration in cultured T cells obtained directly from people living with HIV, as well as engineered primary T cells and cell lines and showed that the site of integration has a dominant effect on the transcriptional activity of intact HIV-1 proviruses in the latent reservoir
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Paper (PMID 39141127) ↗
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