STAG2 Mutations Reshape the Cohesin-Structured Spatial Chromatin Architecture to Drive Gene Regulation in Acute myeloid Leukemia [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 299 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 299 samples: 284 distinct titles, 15 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemiaCell reports · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE268031_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1114079. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 299 sample titles: 284 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8284159 ChIP_AML_ctr_9873_Rad21
- GSM8284160 ChIP_AML_ctr_10156_Rad21
- GSM8284161 ChIP_AML_ctr_11374_Rad21
- GSM8284162 ChIP_AML_ctr_14094_Rad21
- GSM8284163 ChIP_AML_ctr_16911_Rad21
- GSM8284164 ChIP_AML_ctr_18136_Rad21
- GSM8284165 ChIP_AML_ctr_18367_Rad21
- GSM8284166 ChIP_AML_ctr_18519_Rad21
- GSM8284167 ChIP_AML_ctr_19049_Rad21
- GSM8284168 ChIP_AML_ctr_19284_Rad21
- GSM8284169 ChIP_AML_ctr_19405_Rad21
- GSM8284170 ChIP_AML_ctr_19416_Rad21
- GSM8284171 ChIP_AML_ctr_19504_Rad21
- GSM8284172 ChIP_AML_ctr_20180_Rad21
- GSM8284173 ChIP_AML_ctr_20458_Rad21
- GSM8284174 ChIP_AML_ctr_20899_Rad21
- GSM8284175 ChIP_AML_ctr_21047_Rad21
- GSM8284176 ChIP_AML_ctr_21290_Rad21
- GSM8284177 ChIP_AML_ctr_22023_Rad21
- GSM8284178 ChIP_AML_ctr_22759_Rad21
- GSM8284179 ChIP_AML_ctr_22874_Rad21
- GSM8284180 ChIP_AML_Rad21_23039_Rad21
- GSM8284181 ChIP_AML_Rad21_26830_Rad21
- GSM8284182 ChIP_AML_Rad21_27650_Rad21
- GSM8284183 ChIP_AML_Rad21_28420_Rad21
- GSM8284184 ChIP_AML_Rad21_29047_Rad21
- GSM8284185 ChIP_AML_Rad21_29992_Rad21
- GSM8284186 ChIP_AML_Rad21_38455_Rad21
- GSM8284187 ChIP_AML_Rad21_UKR186_Rad21
- GSM8284188 ChIP_AML_Rad21_AML0117_Rad21
- GSM8284189 ChIP_AML_SA2_9708_Rad21
- GSM8284190 ChIP_AML_SA2_15365_Rad21
- GSM8284191 ChIP_AML_SA2_15640_Rad21
- GSM8284192 ChIP_AML_SA2_19142_Rad21
- GSM8284193 ChIP_AML_SA2_22464_Rad21
- GSM8284194 ChIP_AML_SA2_22525_Rad21
- GSM8284195 ChIP_AML_SA2_24743_Rad21
- GSM8284196 ChIP_AML_SA2_25458_Rad21
- GSM8284197 ChIP_AML_SA2_27396_Rad21
- GSM8284198 ChIP_AML_SA2_27493_Rad21
+ 259 more — browse all 299 samples with per-sample file links →
- GSE268035 STAG2 Mutations Reshape the Cohesin-Structured Spatial Chromatin Architecture to Drive Gene Regulation in Acute myeloid Leukemia 541 samples shares stag2, cohesin-structured, architecture, mutations, chromatin, leukemia, reshape
- GSE240343 STAG2 mutations and 3D genome organization, chromatin loops, and polycomb signaling in glioblastoma multiforme 20 samples shares stag2, mutations, chromatin
- GSE278192 Pivotal Role of the NuRD Complex in Remodeling Chromatin Environment and Maintaining Genome Architecture at CTCF Sites [HEK293T ChIP-seq] 45 samples shares architecture, chromatin, chip-seq
- GSE337829 Integrated single-cell profiling of RNA and DNA interactomes reveals targetable chromatin architectures in cancer [ChIP-Seq] 32 samples shares architecture, chromatin, chip-seq
- GSE188175 Pivotal Role of the NuRD Complex in Remodeling Chromatin Environment and Maintaining Genome Architecture at CTCF Sites [ChIP-Seq] 28 samples shares architecture, chromatin, chip-seq
- GSE314776 Decoding 3D chromatin architecture reveals distinct enhancer classes underlying hierarchical gene regulation in prostate cancer [ChIP-Seq] 24 samples shares architecture, chromatin, chip-seq
- GSE215328 Pivotal Role of the NuRD Complex in Remodeling Chromatin Environment and Maintaining Genome Architecture at CTCF Sites [hESC_H9_d049_ChIP_Seq] 135 samples shares architecture, chromatin
- GSE314930 Cohesin mutations suppress HLA class II gene expression to promote immune evasion during the progression to acute leukemia in children with Down syndrome [CUT&Run] 72 samples shares mutations, leukemia
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.