GEO series
Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development (MLT2A1 subfamily KD in 4C and 8C embryos)
GSE268184
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/01/24
GPL24676
Summary
MLT2A1 was highly and specifically expressed in human totipotent embryos. To unveil the function and biological significance of MLT2A1 in regulating human totipotent embryo development and human zygotic genome activation, RNA-seq was performed for MLT2A1 KD and Ctrl KD 4-Cell and 8-Cell embryos.
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