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Bulk RNA-seq of siGFPT2 and NC grouped H1975 cells

GSE269440 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/06/10 Platform GPL24676
Summary
In the evolving field of cancer immunotherapy, EGFR-mutated NSCLC presents a significant challenge, demonstrating marked resistance to established treatments. An effective method to counter this resistance remains elusive. Through comprehensive genetic and pharmacological analyses across various models, we have identified glutamine fructose-6-phosphate transaminase 2 (GFPT2) as a key facilitator of immune evasion in EGFR-mutated NSCLC.
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Direct links to NCBI, no account and no request form: the whole study as GSE269440_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1121924 and SRA study SRP512788. Searching any of these in the dataset finder brings you back here.

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