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Effect of chronic epinephrine exposure on gene expression in MIN6 cells

GSE269666 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/07/17 Platform GPL24247
Summary
Chronic exposure to epinephrine enhances the compensatory insulin secretion in MIN6 cells while persistently inhibiting cell proliferation. The molecular mechanisms underlying these phenomena were investigated through transcriptome sequencing, which identified differential mRNA transcriptional expression. This analysis has uncovered the pivotal signaling pathways that govern cellular function and destiny.
Published in
Chronic Epinephrine-Induced Endoplasmic Reticulum and Oxidative Stress Impairs Pancreatic β-Cells Function and Fate
Zhang R, Yao B, Li R et al. · International journal of molecular sciences 2024 · PMID 39000139 · doi:10.3390/ijms25137029
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Also filed as BioProject PRJNA1123195. Searching any of these in the dataset finder brings you back here.

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