GEO series
"Hepatocyte growth factor has a unique function in keratinocytes that differs from IL-17A and TNF-aand may contribute to the severity of hidradenitis suppurativa.”
GSE269700
Homo sapiens
Expression profiling by high throughput sequencing
24 samples
2024/07/10
GPL24676
Summary
The goal is To examine the effects of four cytokines, HGF, IL-17A, TNF-a, and IL-22, on keratinocytes and compare them to the transcriptomes of HS skin. To examine the expression and localization of HGF, lesional skin samples from patients with HS were investigated by immunohistochemical staining and single cell data analysis. Transcriptome analysis of RNA from keratinocytes stimulated with each cytokine was performed and compared to those of HS lesions.
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Paper (PMID 39038532) ↗
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