The pioneer transcription factor PBX as a downstream target of MNX1 [ATAC]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 10 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 5 × FLC_emptyvectorcontrol_ATAC vs 5 × FLC_MNX1_ATACGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Role of MNX1-mediated histone modifications and PBX gene family in MNX1-induced leukemogenesisScientific reports · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269913_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1124117 and SRA study SRP514044. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8330333 FLC_emptyvectorcontrol_ATAC_1 FLC_emptyvectorcontrol_…
- GSM8330334 FLC_emptyvectorcontrol_ATAC_2 FLC_emptyvectorcontrol_…
- GSM8330335 FLC_emptyvectorcontrol_ATAC_3 FLC_emptyvectorcontrol_…
- GSM8330336 FLC_emptyvectorcontrol_ATAC_4 FLC_emptyvectorcontrol_…
- GSM8330337 FLC_emptyvectorcontrol_ATAC_5 FLC_emptyvectorcontrol_…
- GSM8330338 FLC_MNX1_ATAC_1 FLC_MNX1_ATAC
- GSM8330339 FLC_MNX1_ATAC_2 FLC_MNX1_ATAC
- GSM8330340 FLC_MNX1_ATAC_3 FLC_MNX1_ATAC
- GSM8330341 FLC_MNX1_ATAC_4 FLC_MNX1_ATAC
- GSM8330342 FLC_MNX1_ATAC_5 FLC_MNX1_ATAC
- GSE269910 The pioneer transcription factor PBX as a downstream target of MNX1 [ACT] 55 samples shares mnx1, pbx, transcription, downstream, pioneer, factor, target
- GSE281037 Large-scale transcriptomic analyses reveal downstream target genes of ZFY1 and ZFY2 transcription factors in male germ cells 48 samples shares transcription, downstream, factor, target
- GSE294772 Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging [snATAC-Seq] [10X Multiome] 142 samples shares atac, transcription, factor
- GSE296438 Transcription factor NFYA directs male meiotic entry by facilitating accessible chromatin at the promoters of genes expressed during meiosis [scRNA-seq & scATAC-seq] 10 samples shares atac, transcription, factor
- GSE326173 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [ChIP-seq] 42 samples shares transcription, factor, target
- GSE283906 RXR-Mediated Remodeling of Transcriptional and Chromatin Landscapes in APP Mouse Brain: Insights from Integrated Single-Cell RNA and ATAC Profiling 10 samples shares atac, transcription
- GSE299995 Transcriptional control of Sulf1 by WT1 primes epicardial signalling and fate by modifying extracellular heparan sulfate status [ATAC-Seq] 4 samples shares atac, transcription
- GSE327645 BACH1 acts as a pioneer repressor to enable macrophage plasticity and adaptation across tissues and inflammatory contexts [RNA-seq/ATAC-seq] 28 samples shares atac, pioneer
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.