Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms (main experiment)
RNA-seq (gene expression) · human · 112 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 112 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythmseLife · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270288_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1126131 and SRA study SRP515002. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 112 more — browse all 112 samples with per-sample file links →
- GSE270289 Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms (preliminary experiment) 96 samples shares age-associated, blood-borne, experiment, mediating, circadian, evidence, factors, changes
- GSE270290 Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms 208 samples shares age-associated, blood-borne, mediating, circadian, evidence, factors, changes
- GSE262619 Characteristics of Age-Associated Changes in the Whole Transcriptome of Human Peripheral Blood Leukocytes and Establishment of an Aging Clock 35 samples shares age-associated, changes
- GSE247830 Experimental and Computational Insights into the Mechanism that CHRONO Regulates the Circadian Clock 9 samples shares experiment, circadian
- GSE237793 Experimental and Computational Insights into the Mechanism that CHRONO Regulates the Circadian Clock 16 samples shares experiment, circadian
- GSE261277 Inflammation of the Nasal Mucosa is Associated with Susceptibility to Experimental Pneumococcal Challenge in Older Adults 115 samples shares experiment
- GSE155237 RNAseq of nasal cells from pre-symptomatic volunteers experimentally infected with RSV 78 samples shares experiment
- GSE250139 Probing liver injury induced by thioacetamide in human in vitro pooled hepatocyte experiments 75 samples shares experiment
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.