← BioTransfer GEO Dataset Finder
GEO series

A high-temporal-resolution single-cell transcriptomic atlas of pre- to post-implantation transition in mouse embryogenesis

GSE270803 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/07/30 Platform GPL34328
Summary
Embryo implantation is a pivotal phase in early mammalian embryonic development. However, the mechanisms guiding the embryos from pre- to post-implantation remain largely elusive. Here, we present a comprehensive transcriptomics atlas of mouse embryo implantation, characterized with high temporal resolution. We collected mouse embryos at distinct stages— before, during, and after implantation— and performed single-cell RNA sequencing. Our analysis of 22,171 single-cell transcriptomes elucidates the developmental trajectories encompassing the entire implantation process.
Published in
Basement membrane perforations guide anterior-posterior axis formation
Chen DY, Claussen NH, Titus S et al. · Nature communications 2025 · PMID 40695803 · doi:10.1038/s41467-025-61441-6
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE270803_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1128541 and SRA study SRP516202. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.