Toggling of BRD4 functions is triggered through its phosphorylation by JNK [RNAseq-JQ1]
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Phosphorylation by JNK switches BRD4 functionsMolecular cell · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270887_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1128696 and SRA study SRP516310. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE252980 Toggling of BRD4 functions is triggered through its phosphorylation by JNK [RNA-seq] 18 samples shares brd4, jnk, phosphorylation, functions, triggered, toggling
- GSE252982 Toggling of BRD4 functions is triggered through its phosphorylation by JNK. 52 samples shares brd4, jnk, phosphorylation, functions, triggered, toggling
- GSE252981 Toggling of BRD4 functions is triggered through its phosphorylation by JNK [ChIP-seq] 22 samples shares brd4, jnk, phosphorylation, functions, triggered, toggling
- GSE272018 BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection 15 samples shares brd4, functions
- GSE267369 Elevating PLK1 Overcomes BETi-Resistance in Prostate Cancer via Triggering BRD4 Phosphorylation-dependent Degradation in Mitosis [ChIP-seq] 14 samples shares brd4, phosphorylation
- GSE252349 H3S10-phosphorylation spreading in mitosis stably preserves 3D chromatin structure and functions 27 samples shares phosphorylation, functions
- GSE308299 JNK knockdown enhances CAR-T cell cytotoxicity through NFATc1 in preclinical models of ovarian cancer 12 samples shares jnk
- GSE288360 Dominant interfering CARD11 variants disrupt JNK signaling to promote GATA3 expression in T cells 60 samples shares jnk
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.