GEO series
RNA-seq of live cell 3-D models with engineered genetic sub-types of lung cancer
GSE271368
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2024/07/25
GPL21290
Summary
An experimental system was designed to screen for targetable signaling pathways linked to early 3D invasion in molecular subtypes, TP53 and LKB1, of KRAS-driven lung adenocarcinoma (LUAD). Live-cell imaging of human bronchial epithelial cells during 3D invasion was combined with RNA transcriptome profiling shown here.
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Paper (PMID 39207369) ↗
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