GEO series
Shivering improves metabolic health in adults with overweight or obesity
GSE271452
Homo sapiens
Expression profiling by high throughput sequencing
30 samples
2024/09/24
GPL23227
Summary
Mild cold acclimation increases insulin sensitivity and previous studies indicate that some level of muscle contraction is essential for provoking this effect. Here, 15 adults with overweight or obesity, the majority of which had impaired glucose tolerance (n=9), were intermittently cold exposed for 10 consecutive days to induce 1 hour of shivering per day. Cold acclimation with shivering improved oral glucose tolerance, blood pressure, fasting glucose, triglyceride, and non-esterified free-fatty acid concentrations, and may thus represent a novel lifestyle approach for the prevention and treatment of obesity-related metabolic disorders.
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Paper (PMID 39643644) ↗
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