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Effect of hypoxia on gene expression in Hep3B cells

GSE271612 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/04/17 Platform GPL24676
Summary
Hypoxic microenvironment plays a critical role in solid tumor progression. More and more protein coding and non-coding RNA genes have been identified as hypoxia-regulated genes in HCC. Thus, we attempted to identify more novel hypoxia-regulated genes in HCC with Hep3B cells exposed to 20% or 1% oxygen.
Published in
A novel hypoxia-induced lncRNA, SZT2-AS1, boosts HCC progression by mediating HIF heterodimerization and histone trimethylation under a hypoxic microenvironment
Liu R, Guo Y, Wang L et al. · Cell death and differentiation 2025 · PMID 39572656 · doi:10.1038/s41418-024-01419-x
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Also filed as BioProject PRJNA1132287 and SRA study SRP518227. Searching any of these in the dataset finder brings you back here.

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