Transcriptomics of FFPE-derived primary brain tumours
RNA-seq (gene expression) · human · 153 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- GlioblastomaThis series is part of our curated briefing on it.
- Samples
- 153 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcriptomics and epigenomics datasets of primary brain cancers in formalin-fixed paraffin embedded formatScientific data · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272042_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1134745 and SRA study SRP519395. Searching any of these in the dataset finder brings you back here.
The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Sample titles run Sample 31 … Sample 413 and carry no group information.
- GSM8391641 Sample 31
- GSM8391642 Sample 32
- GSM8391643 Sample 42
- GSM8391644 Sample 73
- GSM8391645 Sample 81
- GSM8391646 Sample 95
- GSM8391647 Sample 158
- GSM8391648 Sample 166
- GSM8391649 Sample 199
- GSM8391650 Sample 208
- GSM8391651 Sample 214
- GSM8391652 Sample 236
- GSM8391653 Sample 249
- GSM8391654 Sample 253
- GSM8391655 Sample 416
- GSM8391656 Sample 466
- GSM8391657 Sample 3
- GSM8391658 Sample 12
- GSM8391659 Sample 16
- GSM8391660 Sample 19
- GSM8391661 Sample 29
- GSM8391662 Sample 46
- GSM8391663 Sample 58
- GSM8391664 Sample 61
- GSM8391665 Sample 91
- GSM8391666 Sample 105
- GSM8391667 Sample 110
- GSM8391668 Sample 128
- GSM8391669 Sample 184
- GSM8391670 Sample 227
- GSM8391671 Sample 36
- GSM8391672 Sample 41
- GSM8391673 Sample 66
- GSM8391674 Sample 67
- GSM8391675 Sample 92
- GSM8391676 Sample 102
- GSM8391677 Sample 254
- GSM8391678 Sample 255
- GSM8391679 Sample 346
- GSM8391680 Sample 363
+ 113 more — browse all 153 samples with per-sample file links →
- GSE231555 Splicing and gene expression changes in cell lines treated with splicing switching oligonucleotide targeting TRA2B 46 samples same disease briefing
- GSE112648 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 18 samples same disease briefing
- GSE131928 single cell RNA-seq analysis of adult and paediatric IDH-wildtype Glioblastomas 2 samples same disease briefing
- GSE107560 Ivy Glioblastoma Atlas Project 305 samples same disease briefing
- GSE13041 Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age 267 samples same disease briefing
- GSE10878 Integrative Genome-wide Analysis of Glioblastoma. 60 samples same disease briefing
- GSE112650 SOX4/11 Enhances NGN2 Reprogramming Glioblastoma Cells into Neuron Cells by Modulating RhoA and CDC42/RAC1 Pathway Activity 30 samples same disease briefing
- GSE112645 SOXC factors as suppressors modulate Rho activity to promote neuronal reprogramming of human glioblastoma cells 12 samples same disease briefing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.