SWI/SNF complex ATPase activity supports normal syncytiotrophoblast differentiation and shields from EVT differentiation [ATAC-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Activity of the SWI/SNF complex is indispensable for syncytiotrophoblast formationDevelopment (Cambridge, England) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272427_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1136854 and SRA study SRP520511. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8401960 1_SR
- GSM8401961 1_SRBRM
- GSM8401962 1_ST
- GSM8401963 1_STBRM
- GSM8401964 2_SR
- GSM8401965 2_SRBRM
- GSM8401966 2_ST
- GSM8401967 2_STBRM
- GSM8401968 3_SR
- GSM8401969 3_SRBRM
- GSM8401970 3_ST
- GSM8401971 3_STBRM
- GSM8401972 4_SR
- GSM8401973 4_SRBRM
- GSM8401974 4_ST
- GSM8401975 4_STBRM
- GSM8401976 5_SR
- GSM8401977 5_SRBRM
- GSM8401978 5_ST
- GSM8401979 5_STBRM
- GSE256317 SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity [ATAC-Seq] 32 samples shares swi, snf, activity, atac-seq, complex
- GSE256316 SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity [ChIP-Seq] 121 samples shares swi, snf, activity, complex
- GSE262057 LncRNA adapters determine SWI/SNF complex occupancy at gene regulatory elements [ATAC-seq] 12 samples shares swi, snf, atac-seq, complex
- GSE249258 Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer 24 samples shares swi, snf, activity, complex
- GSE180483 PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression [ChIP-seq] 88 samples shares swi, snf, complex
- GSE270948 ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency [ATAC-Seq] 46 samples shares swi, snf, atac-seq
- GSE262093 SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma [human ChIP-seq] 14 samples shares swi, snf, complex
- GSE328504 CBFA2T3-GLIS2 fusion-mediated mSWI/SNF chromatin remodeler disruption generates cancer-specific dependencies in AMKL [ATAC-Seq] 11 samples shares swi, snf, atac-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.