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Crnic Institute - Trisomy 21 Model Atlas: Spatial Transcriptomics of 9-month old mouse brain tissue

GSE272845 Mus musculus Expression profiling by high throughput sequencing; Other 4 samples Submitted 2025/07/23 Platform GPL24247
Summary
Analysis of steady-state mRNA levels in mouse brain hippocampus tissue at 9 months from wild-type C57BL/6J, Dp16, 5xFAD, and 5xFAD-Dp16 mice.
Published in
Interferon signaling modulates Down syndrome-associated Alzheimer's disease pathology in a mouse model
Araya P, Niemeyer B, Schade K et al. · iScience 2025 · PMID 40799393 · doi:10.1016/j.isci.2025.113130
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Also filed as BioProject PRJNA1139106 and SRA study SRP521585. Searching any of these in the dataset finder brings you back here.

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