Distinct NK Cell Function and Gene Expression in Children with Acute Lymphoblastic Leukemia in Remission Before and After Acute Exercise
RNA-seq (gene expression) · human · 36 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Acute lymphoblastic leukemiaThis series is part of our curated briefing on it.
- Samples
- 36 samples: 36 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory studyFrontiers in immunology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272928_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1139316 and SRA study SRP521807. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 36 sample titles: 36 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8415178 CONT 51 BASELINE
- GSM8415179 CONT 51 PEAK
- GSM8415180 CONT 52 BASELINE
- GSM8415181 CONT 52 PEAK
- GSM8415182 CONT 53 BASELINE
- GSM8415183 CONT 53 PEAK
- GSM8415184 CONT 54 BASELINE
- GSM8415185 CONT 54 PEAK
- GSM8415186 CONT 55 BASELINE
- GSM8415187 CONT 55 PEAK
- GSM8415188 CONT 56 BASELINE
- GSM8415189 CONT 56 PEAK
- GSM8415190 CONT 57 BASELINE
- GSM8415191 CONT 57 PEAK
- GSM8415192 CONT 58 BASELINE
- GSM8415193 CONT 58 PEAK
- GSM8415194 CONT 59 BASELINE
- GSM8415195 CONT 59 PEAK
- GSM8415196 ALL02 BASELINE
- GSM8415197 ALL02 PEAK
- GSM8415198 ALL03 BASELINE
- GSM8415199 ALL03 PEAK
- GSM8415200 ALL05 BASELINE
- GSM8415201 ALL05 PEAK
- GSM8415202 ALL07 BASELINE
- GSM8415203 ALL07 PEAK
- GSM8415204 ALL08 BASELINE
- GSM8415205 ALL08 PEAK
- GSM8415206 ALL09 BASELINE
- GSM8415207 ALL09 PEAK
- GSM8415208 ALL10 BASELINE
- GSM8415209 ALL10 PEAK
- GSM8415210 ALL11 BASELINE
- GSM8415211 ALL11 PEAK
- GSM8415212 ALL12 BASELINE
- GSM8415213 ALL12 PEAK
- GSE115656 Alternative splicing analysis of pediatric B-cell acute lymphoblastic leukemia compared to normal bone marrow derived pro-B cells 38 samples same disease briefing · shares lymphoblastic, leukemia, acute
- GSE12995 Expression data for diagnosis acute lymphoblastic leukemia samples 175 samples same disease briefing · shares lymphoblastic, leukemia, acute
- GSE160298 The chromatin accessibility landscape of T-Cell Acute Lymphoblastic Leukemia 80 samples same disease briefing · shares lymphoblastic, leukemia, acute
- GSE13425 Expression data from ALL patients included in the set used to construct a classification signature (COALL cohort) 190 samples same disease briefing
- GSE154675 PHF6 Interacts with LMO2 During Normal Haematopoiesis and in Leukaemia and Regulates the Level of Gene Expression and Genome Integrity 41 samples same disease briefing
- GSE18198 Expression profile of human T-ALL cell lines treated with DMSO or SAHM1 12 samples same disease briefing
- GSE193713 Genome-wide maps of chromatin state for histone modifications and chromatin remodeling factors in WT and PHF6-KO conditions in Jurkat T-ALL cells. 20 samples same disease briefing
- GSE272023 CpG island methylator phenotype classification improves risk assessment in pediatric T-cell Acute Lymphoblastic Leukemia [RNA-seq] 111 samples shares lymphoblastic, leukemia, acute
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.