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Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis - Monocyte

GSE273106 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/07/25 Platform GPL18573
Summary
Obesity and altered lipid metabolism are associated with colorectal cancer (CRC). In this context, the presence of colonic lipid-engulfed macrophages (foam cells, FC) may hinder protective T cell immunity, thus favoring gut carcinogenesis.
Published in
Cancer-associated foam cells hamper protective T cell immunity and favor tumor progression in human colon carcinogenesis
Daveri E, Vergani B, Lalli L et al. · Journal for immunotherapy of cancer 2024 · PMID 39395839 · doi:10.1136/jitc-2024-009720
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Also filed as BioProject PRJNA1140184 and SRA study SRP522220. Searching any of these in the dataset finder brings you back here.

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