Understanding the dosage-dependent role of Dicer1 in thyroid tumorigenesis [2]
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Understanding the Dosage-Dependent Role of Dicer1 in Thyroid TumorigenesisInternational journal of molecular sciences · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273204_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1140599 and SRA study SRP522485. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE273129 Understanding the dosage-dependent role of Dicer1 in thyroid tumorigenesis 18 samples shares dicer1, dosage-dependent, understanding, tumorigenesis, thyroid
- GSE299101 DICER1 dysregulation triggers miRNA reprogramming, promotes mesenchymal cell fates and slows TNBC tumorigenic phenotypes 12 samples shares dicer1
- GSE264566 Human DICER1+/- RMS tumors are enriched for neutrophils [bulk RNA-seq] 8 samples shares dicer1
- GSE328604 DICER1-related tumor predisposition mutations lead to a gain of 3p-miRNA function, HERVH activity and increased metastatic potential 5 samples shares dicer1
- GSE313183 DICER1 syndrome-associated mutations lead to 3p-miRNA gain of function and increased metastatic potential 5 samples shares dicer1
- GSE297086 SLAM-seq reveals the promotive role of NDRG1 in Fusobacterium nucleatum-induced Tumorigenesis in Colorectal Cancer. 12 samples shares tumorigenesis
- GSE151530 Understanding tumor evolution and its clonality by single-cell transcriptomic analysis in liver cancer 46 samples shares understanding
- GSE278183 Understanding the early molecular changes associated with radiation therapy – a preliminary bulk RNA sequencing study 42 samples shares understanding
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.