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The potential impact of VHL on chromatin accessibility using the assay for ATAC-seq in Caki-1 cells.

GSE273354 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2026/01/23 Platform GPL24676
Summary
To investigate the potential impact of VHL on chromatin accessibility, the assay for transposase-accessible chromatin with high throughput sequencing (ATAC-seq) was performed in renal cell carcinoma cells.The VHL wild-type Caki-1 cells were used to generate control or VHL knockout cells by CRISPR/Cas9-mediated genome editing (sgCTR and sgVHL Caki-1 cells).Following ATAC-seq, DNAs were amplified using non-biased conditions, labeled, and sequenced with Illumina NovaSeq 6000.
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Also filed as BioProject PRJNA1141477 and SRA study SRP522839. Searching any of these in the dataset finder brings you back here.

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