Effect of feeding on gene expression in HEK-293E cells either treated with Torin1 or not.
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicingMolecular cell · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273388_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1141525 and SRA study SRP522918. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8427540 S_1 S
- GSM8427541 S_2 S
- GSM8427542 S_3 S
- GSM8427543 F1_1 F1
- GSM8427544 F1_2 F1
- GSM8427545 F1_3 F1
- GSM8427546 F4_1 F4
- GSM8427547 F4_2 F4
- GSM8427548 F4_3 F4
- GSM8427549 ST_1 ST
- GSM8427550 ST_2 ST
- GSM8427551 ST_3 ST
- GSM8427552 F1T_1 F1T
- GSM8427553 F1T_2 F1T
- GSM8427554 F1T_3 F1T
- GSM8427555 F4T_1 F4T
- GSM8427556 F4T_2 F4T
- GSM8427557 F4T_3 F4T
- GSE293037 Bulk transcriptome analysis of wildtype, TREM2 knockout, GPR34 knock-out or TREM2/GPR34 double knock-out iPSC-derived human microglia treated either with PBS or myelin. 32 samples shares treated, either
- GSE292059 Inflammatory Epithelial and Macrophage Pathways Underlie Residual Asthma Exacerbations in Urban Children Treated with Mepolizumab 965 samples shares treated
- GSE234209 Gene expression profile at single cell level of immune cells and gastric cancer cells from multipoint biopsy samples of 2 gastric cancer patients treated by PD-1 antibody-based therapy 12 samples shares treated
- GSE315664 Gene expression profile of antisense oligonucleotide-treated Neural Progenitors from controls and Schinzel-Giedion Syndrome cases 60 samples shares treated
- GSE269374 Microprotein-Encoding RNA Regulation in Cells Treated with Pro-inflammatory and Pro-Fibrotic Stimuli (RNA-Seq colon cell lines) 54 samples shares treated
- GSE222412 Genome-wide gene expression profiling of macrophages treated with novel 1,2,4-oxadiazole scaffold-based compounds 48 samples shares treated
- GSE249009 RNA sequencing analysis of isoginkgetin and thapsigargin treated HCT116 and HCT116 ATF4 deficient cells 48 samples shares treated
- GSE281511 RNA seq of liver cancer cells treated with different concentration gradients of Thapsigargin (TG), Tunicamycin (TM), and FCCP 44 samples shares treated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.