Gene expression profiles of platinum-resistant high-grade serous ovarian carcinoma
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 20 × RNA-Seq - PatientGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Overcoming platinum-resistant ovarian cancer targeting the activated JAK-STAT pathways via extracellular vesiclesCommunications biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE273637_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1142545 and SRA study SRP523497. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 1 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8434256 RNA-Seq - Patient_1 RNA-Seq - Patient
- GSM8434257 RNA-Seq - Patient_2 RNA-Seq - Patient
- GSM8434258 RNA-Seq - Patient_3 RNA-Seq - Patient
- GSM8434259 RNA-Seq - Patient_4 RNA-Seq - Patient
- GSM8434260 RNA-Seq - Patient_5 RNA-Seq - Patient
- GSM8434261 RNA-Seq - Patient_6 RNA-Seq - Patient
- GSM8434262 RNA-Seq - Patient_7 RNA-Seq - Patient
- GSM8434263 RNA-Seq - Patient_8 RNA-Seq - Patient
- GSM8434264 RNA-Seq - Patient_9 RNA-Seq - Patient
- GSM8434265 RNA-Seq - Patient_10 RNA-Seq - Patient
- GSM8434266 RNA-Seq - Patient_11 RNA-Seq - Patient
- GSM8434267 RNA-Seq - Patient_12 RNA-Seq - Patient
- GSM8434268 RNA-Seq - Patient_13 RNA-Seq - Patient
- GSM8434269 RNA-Seq - Patient_14 RNA-Seq - Patient
- GSM8434270 RNA-Seq - Patient_15 RNA-Seq - Patient
- GSM8434271 RNA-Seq - Patient_16 RNA-Seq - Patient
- GSM8434272 RNA-Seq - Patient_17 RNA-Seq - Patient
- GSM8434273 RNA-Seq - Patient_18 RNA-Seq - Patient
- GSM8434274 RNA-Seq - Patient_19 RNA-Seq - Patient
- GSM8434275 RNA-Seq - Patient_20 RNA-Seq - Patient
- GSE274659 Platinum-resistant high-grade serous ovarian carcinoma 68 samples shares platinum-resistant, high-grade, ovarian, serous
- GSE282004 Tumor Exosome-transmitted LncRNA CATED Promotes Platinum-resistant in High-grade Serous Ovarian Cancer 17 samples shares platinum-resistant, high-grade, ovarian, serous
- GSE285827 PARP inhibitors differentially regulate immune responses in distinct genetic backgrounds of high-grade serous tubo-ovarian carcinoma 18 samples shares high-grade, ovarian, serous
- GSE286888 Comparative gene expression profiling of high-grade serous ovarian cancer cells exposed to cisplatin or CX-5461 60 samples shares high-grade, ovarian, serous
- GSE268514 Integrative genomic analysis of Korean high-grade serous ovarian cancer 161 samples shares high-grade, ovarian, serous
- GSE292142 Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma [RNA-Seq] 23 samples shares high-grade, ovarian, serous
- GSE224392 Immunotherapies that repolarize macrophages and regulatory T cells enhance the effect of chemotherapy in high-grade serous ovarian cancer (Human) 21 samples shares high-grade, ovarian, serous
- GSE247982 The chromatin landscape of high-grade serous ovarian cancer metastasis identifies potential regulatory drivers of chemoresistant tumour cells 10 samples shares high-grade, ovarian, serous
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.