GEO series
Whole transcriptome analysis reveals T cell signaling activation in septic patients with thrombocytopenia
GSE273700
Homo sapiens
Expression profiling by high throughput sequencing
104 samples
2026/01/28
GPL24676
Summary
Sepsis, a life-threatening condition triggered by a dysregulated immune response to infection, remains one of the leading causes of mortality worldwide. Thrombocytopenia, a common sepsis complication, is linked to poor outcomes and reflects disease severity and specific immunological changes affecting patient outcomes. This study aims to elucidate this relationship using whole-transcriptome RNA sequencing (RNA-Seq) in intensive care unit (ICU) patients with sepsis.
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Paper (PMID 41444326) ↗
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