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Cardiomyocyte development from human induced pluripotent stem cells (iPSC)

GSE273793 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/09/01 Platform GPL24676
Summary
Induced-pluripotent stem cell-derived cardiomyocyte (IPSC-CM) models can improve understanding of pathophysiology through disease modelling and can be used for cardiotoxicity screening of drugs, ultimately reducing reliance on animal models; however these models have not been extensively functionally characterised, which was the aim of this study. A contracting IPSC-CM model was generated and characterised for atrial and ventricle-specific cardiac gene expression with RNAsequencing. These data are to be correlated with functional assays.
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Direct links to NCBI, no account and no request form: the whole study as GSE273793_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1143066 and SRA study SRP523761. Searching any of these in the dataset finder brings you back here.

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