A Repressive Type of TEAD4 Condensation and Engineering a Glue Peptide Therapy Against Cancer [Cut&Tag_T4]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 11 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 11 samples: 3 × GLUP vs 3 × TEAD4KO vs 3 × GLUP_TEAD4KO vs 2 × CtrlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE274201_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1145389 and SRA study SRP524880. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 4 replicated groups read from 11 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8445027 Ctrl1 Ctrl
- GSM8445028 Ctrl3 Ctrl
- GSM8445029 GLUP1 GLUP
- GSM8445030 GLUP2 GLUP
- GSM8445031 GLUP3 GLUP
- GSM8445032 TEAD4KO_1 TEAD4KO
- GSM8445033 TEAD4KO_2 TEAD4KO
- GSM8445034 TEAD4KO_3 TEAD4KO
- GSM8445035 GLUP_TEAD4KO_1 GLUP_TEAD4KO
- GSM8445036 GLUP_TEAD4KO_2 GLUP_TEAD4KO
- GSM8445037 GLUP_TEAD4KO_3 GLUP_TEAD4KO
- GSE244420 A Repressive Type of TEAD4 Condensation and Engineering a Glue Peptide Therapy Against Cancer 14 samples shares tead4, condensation, engineering, repressive, peptide, therapy, against, type
- GSE255046 A Repressive Type of TEAD4 Condensation and Engineering a Glue Peptide Therapy Against Cancer [RNA-Seq_TEAD4KO] 12 samples shares tead4, condensation, engineering, repressive, peptide, therapy, against, type
- GSE309802 OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumors 78 samples shares engineering, therapy, against
- GSE310267 OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumors 36 samples shares engineering, therapy, against
- GSE303471 JMJD3 and UTX as Key Targets for Gene-Modified Mesenchymal Stem Cell Therapy in Cartilage Tissue Engineering 36 samples shares engineering, therapy
- GSE288846 Engineering a novel HSV-1 strain for oncolytic therapy of solid tumors 16 samples shares engineering, therapy
- GSE338343 Engineering hematopoietic stem and progenitor cells to generate red blood cells as viral traps against HIV-1 12 samples shares engineering, against
- GSE299321 Implications of TEAD4 in Metabolic Processes of Gastric Cancer [RNA-Seq] 15 samples shares tead4
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.