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In vivo Spatial Perturb-Seq in the mouse brain

GSE274447 Mus musculus Other 3 samples Submitted 2025/12/01 Platform GPL28330
Summary
Functional genomics that knocks out individual genes is ideal for investigating gene functions. Examining these perturbations in vivo, within native tissue architecture and with spatial context, is crucial for accurately assessing the impact of genetic modifications both within the cell and on its microenvironment.
Published in
Spatial perturb-seq: single-cell functional genomics within intact tissue architecture
Shen K, Seow WY, Keng CT et al. · Nature communications 2026 · PMID 41723140 · doi:10.1038/s41467-026-69677-6
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Also filed as BioProject PRJNA1146440. Searching any of these in the dataset finder brings you back here.

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