In vitro Examination of Piezo1-TRPV4 Dynamics: Implications for Placental Endothelial Function in Normal and Preeclamptic Pregnancies
RNA-seq (gene expression) · human · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 17 samples: 7 × fpECs term control vs 5 × fpECs early-onset preeclampsia vs 5 × fpECSs preterm controlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- In vitro examination of Piezo1-TRPV4 dynamics: implications for placental endothelial function in normal and preeclamptic pregnanciesAmerican journal of physiology. Cell physiology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE274555_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1147202 and SRA study SRP526525. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 17 samples.
How we read this: 3 replicated groups read from 17 sample titles; they account for 17 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8452803 fpECs early-onset preeclampsia 1 fpECs early-onset preec…
- GSM8452804 fpECs early-onset preeclampsia 2 fpECs early-onset preec…
- GSM8452805 fpECs early-onset preeclampsia 3 fpECs early-onset preec…
- GSM8452806 fpECs early-onset preeclampsia 4 fpECs early-onset preec…
- GSM8452807 fpECs early-onset preeclampsia 5 fpECs early-onset preec…
- GSM8452808 fpECSs preterm control 1 fpECSs preterm control
- GSM8452809 fpECSs preterm control 2 fpECSs preterm control
- GSM8452810 fpECSs preterm control 3 fpECSs preterm control
- GSM8452811 fpECSs preterm control 4 fpECSs preterm control
- GSM8452812 fpECSs preterm control 5 fpECSs preterm control
- GSM8452813 fpECs term control 1 fpECs term control
- GSM8452814 fpECs term control 2 fpECs term control
- GSM8452815 fpECs term control 3 fpECs term control
- GSM8452816 fpECs term control 4 fpECs term control
- GSM8452817 fpECs term control 5 fpECs term control
- GSM8452818 fpECs term control 6 fpECs term control
- GSM8452819 fpECs term control 7 fpECs term control
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.