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Deferasirox, an iron chelator, impacts myeloid differentiation by modulating NF-kB activity via mitochondrial ROS

GSE274956 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2024/09/27 Platform GPL30173
Summary
Deferasirox (DFX) can improve erythropoiesis in patients with MDS. We sought to test how these changes occur and whether myelopoiesis broadly is affected by analyzing neutrophils and neutrophil precursors treated with DFX.
Published in
Deferasirox, an iron chelator, impacts myeloid differentiation by modulating NF-kB activity via mitochondrial ROS
Jeffries NE, Sadreyev D, Trull EC et al. · British journal of haematology 2024 · PMID 39327763 · doi:10.1111/bjh.19782
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Also filed as BioProject PRJNA1148639 and SRA study SRP526680. Searching any of these in the dataset finder brings you back here.

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