PBAF associates with repressed chromatin to enable REST occupancy (RNA-Seq)
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatinbioRxiv : the preprint server for biology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275420_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1150637 and SRA study SRP527912. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
- GSE278549 PBAF associates with repressed chromatin to enable REST occupancy 61 samples shares pbaf, rest, associates, repressed, chromatin, occupancy, enable
- GSE288701 A pathogenic GATA2 zinc finger mutation restricts chromatin occupancy in human erythroid progenitor cells 36 samples shares rest, chromatin, occupancy
- GSE276045 Substrate stiffness dictates unique paths towards proliferative arrest in WI-38 cells [RNA-Seq 1] 178 samples shares rest, rna-seq
- GSE300791 Enhancer Dynamics and Spatial Organization Drive Anatomically Restricted Cellular States in the Human Spinal Cord [scRNA-seq] 20 samples shares rest, rna-seq
- GSE297335 ABHD18 is essential for cardiolipin remodeling and its inhibition restores mitochondrial function in Barth Syndrome [RNA-Seq] 18 samples shares rest, rna-seq
- GSE299954 MeCP2 gene dosage-dependent neurodevelopmentally restricted defects arise by SWI/SNF-mediated aberrant activation of cell fate-determining bivalent genes [RNA-Seq] 18 samples shares rest, rna-seq
- GSE300577 Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation [RNA-seq] 18 samples shares rest, rna-seq
- GSE181946 The PKCα/ZFP64/CSF1 Axis restricts Tumor Response to Anti-PD1 by driving Macrophage M2 Polarization in Hepatocellular Carcinoma [RNA-seq 1] 17 samples shares rest, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.