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Study title: B Cells Promote T Cell Immunosenescence and Mammalian Aging Parameters - B and T Cell Singlet and PIC Single Cell RNA Seq

GSE275466 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/12/31 Platform GPL34290
Summary
The goals of this experiment were two-fold: 1) To understand changes in splenic B and T cells at the transcriptomic level, and 2) to identify unique physically interacting B-T cells and their molecular signatures in young and aged mice.
Published in
B cells drive CD4 T cell immunosenescence and age-associated health decline
Khan S, Chakraborty M, Wu F et al. · Science immunology 2026 · PMID 41616067 · doi:10.1126/sciimmunol.adv7615
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Also filed as BioProject PRJNA1150991 and SRA study SRP528082. Searching any of these in the dataset finder brings you back here.

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