GEO series
Modification of Titanium-based implant materials by Zn-doped calcium phosphate coatings improves corrosion resistance, biomineralization, antibacterial efficacy and immunocompatibility
GSE275792
Homo sapiens
Expression profiling by high throughput sequencing
83 samples
2025/12/04
GPL21697
Summary
Implant-induced chronic inflammation and aseptic implant failure represent serious clinical challenges in orthopedics, dentistry, and reconstructive surgery. Our study aimed to develop an implant material that minimizes acute and chronic inflammation while providing long-term integration properties. We systematically investigated the innate immune responses modulated by the addition of Zn to CaP coatings, using whole transcriptome profiling through RNA sequencing (RNA-Seq).
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Paper (PMID 39880075) ↗
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