GEO series
Glioblastoma tumorspheres treated with perphenazine (PER) and temozolomide (TMZ)
GSE275875
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/03/01
GPL24676
Summary
Glioblastoma (GBM), a primary malignant brain tumor, has a poor prognosis, even with standard treatments such as radiotherapy and chemotherapy. In this study, we explored the anticancer effects of the synergistic combination of perphenazine (PER), a dopamine receptor D2/3 (DRD2/3) antagonist, and temozolomide (TMZ), a standard treatment for GBM, in patient-derived human GBM tumorspheres (TSs).
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Paper (PMID 39392921) ↗
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