GEO series
Clonally expanded targetable natural killer-like T cells seed the aged spinal cord to disrupt wound healing [scGEX and TCR]
GSE275982
Mus musculus
Expression profiling by high throughput sequencing; Other
24 samples
2025/01/12
GPL24247
Summary
CD8+ T cells were found accumulated in the spinal cord preceding (aged) and following spinal cord injury. We used single cell TCR sequencing to analyze the clonality of T cells in the spinal cord and discovered that CD8+ T cells exhibit age and injury-dependent clonal expansion.
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Paper (PMID 39809279) ↗
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