AAV Assembled Capsids Are Produced in Cells Blocked fromFrom Cell Cycle Progression
RNA-seq (gene expression) · human · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 11 samples: 3 × AAV24-GFPpAFn vs 3 × AAV24-GFPpAFp vs 3 × Mock-24-GFPp vs 2 × 293SF-fixedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- AAV Assembled Capsids Are Produced in Cells Blocked From Cell Cycle ProgressionBiotechnology and bioengineering · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276141_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1155159 and SRA study SRP529908. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 4 replicated groups read from 11 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8491856 293SF-fixed replicate 1 293SF-fixed
- GSM8491857 293SF-fixed replicate 2 293SF-fixed
- GSM8491858 AAV24-GFPpAFn replicate 1 AAV24-GFPpAFn
- GSM8491859 AAV24-GFPpAFn replicate 2 AAV24-GFPpAFn
- GSM8491860 AAV24-GFPpAFn replicate 3 AAV24-GFPpAFn
- GSM8491861 AAV24-GFPpAFp replicate 1 AAV24-GFPpAFp
- GSM8491862 AAV24-GFPpAFp replicate 2 AAV24-GFPpAFp
- GSM8491863 AAV24-GFPpAFp replicate 3 AAV24-GFPpAFp
- GSM8491864 Mock-24-GFPp replicate 1 Mock-24-GFPp
- GSM8491865 Mock-24-GFPp replicate 2 Mock-24-GFPp
- GSM8491866 Mock-24-GFPp replicate 3 Mock-24-GFPp
- GSE279022 RNA N6-Methyladenosine (m6A) regulates cell cycle progression in Diffuse Midline Glioma (DMG) and confers sensitivity to FTO inhibition 30 samples shares progression, cycle
- GSE285947 Protein Kinase R regulates pancreatic ductal adenocarcinoma progression by modulating the cell cycle via GADD45A 18 samples shares progression, cycle
- GSE282963 Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity 12 samples shares progression, cycle
- GSE297120 A cytomegalovirus encoded lncRNA blocks cell cycle progression 104 samples shares progression, cycle
- GSE226054 Comprehensive mRNA-sequencing-based characterization of three HEK-293 cell lines during an rAAV production process for Gene Therapy Applications 120 samples shares aav
- GSE244257 Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6 mediated gene editing in hematopoietic stem cells 83 samples shares aav
- GSE334008 CTCF regulates wild-type and recombinant AAV gene expression by shaping viral chromatin [CUT&Run] 47 samples shares aav
- GSE272562 Dynamic activation of rAAV transgene expression by a small molecule that recruits endogenous transcriptional machinery 46 samples shares aav
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.