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Transcriptomic Analysis of Identical Twins with Different Onset Ages of ALD

GSE276153 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/09/06 Platform GPL29480
Summary
Adrenoleukodystrophy (ALD) is a rare X-linked neurogenetic disease caused by mutations in the ABCD1 gene. Currently, the molecular mechanisms underlying the onset and severity of ALD still remain unclear. For mining information on candidate genes associated with onset and severity of ALD, RNA-seq had been executed via using whole blood samples from monozygotic twin families with ALD disease. The information on candidate genes of this research had been considered as the crucial for preliminarily exploring the molecular mechanisms relating to the onset and severity of ALD, which offered novel insights and research directions for mitigating and treating the development of ALD.
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Direct links to NCBI, no account and no request form: the whole study as GSE276153_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1155188 and SRA study SRP529928. Searching any of these in the dataset finder brings you back here.

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