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Compare the loci-specific histone acetylation on the chromatin of FK228 and Class I HDACs YF mutants overexpression

GSE276219 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 8 samples Submitted 2026/03/28 Platform GPL24247
Summary
To compare the H3K27ac effects of FK228 and Class I HDACs YF mutants overexpression and to characterize their inter-dependency, we performed ChIP-seq in AML12 cells in the above-mentioned 4 groups: control, FK228, YF overexpression, and FK228 + YF overexpression.
Published in
Histone deacetylase enzyme activity is not the universal anticancer target of HDAC inhibitors
Rai C, Ruan H, Li X et al. · Signal transduction and targeted therapy 2026 · PMID 42248845 · doi:10.1038/s41392-026-02698-1
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Also filed as BioProject PRJNA1156000 and SRA study SRP530182. Searching any of these in the dataset finder brings you back here.

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