WDR36 regulates trophectoderm differentiation during human preimplantation embryonic development through glycolytic metabolism
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- WDR36 Regulates Trophectoderm Differentiation During Human Preimplantation Embryonic Development Through Glycolytic MetabolismAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276344_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1156759 and SRA study SRP530767. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8496799 D4_Spheroid_Ctrl_Rep1 D4_Spheroid_Ctrl
- GSM8496800 D4_Spheroid_Ctrl_Rep2 D4_Spheroid_Ctrl
- GSM8496801 D4_Spheroid_DOX_Rep1 D4_Spheroid_DOX
- GSM8496802 D4_Spheroid_DOX_Rep2 D4_Spheroid_DOX
- GSM8496803 D6_Blastoid_Ctrl_Rep1 D6_Blastoid_Ctrl
- GSM8496804 D6_Blastoid_Ctrl_Rep2 D6_Blastoid_Ctrl
- GSM8496805 D6_Blastoid_DOX_Rep1 D6_Blastoid_DOX
- GSM8496806 D6_Blastoid_DOX_Rep2 D6_Blastoid_DOX
- GSM8496807 D6_Spheroid_Ctrl_Rep1 D6_Spheroid_Ctrl
- GSM8496808 D6_Spheroid_Ctrl_Rep2 D6_Spheroid_Ctrl
- GSM8496809 D6_Spheroid_DOX_Rep1 D6_Spheroid_DOX
- GSM8496810 D6_Spheroid_DOX_Rep2 D6_Spheroid_DOX
- GSE247631 α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells [RNA-Seq] 16 samples shares trophectoderm, embryonic
- GSE279812 Intercellular crosstalk within human preimplantation lineages regulates Trophectoderm specification 4 samples shares preimplantation, trophectoderm
- GSE270957 α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells [scRNA-Seq 3D] 4 samples shares trophectoderm, embryonic
- GSE247633 α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells [scRNA-Seq 2D] 2 samples shares trophectoderm, embryonic
- GSE247634 α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells 28 samples shares trophectoderm, embryonic
- GSE247630 α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells [ATAC-Seq] 6 samples shares trophectoderm, embryonic
- GSE306470 CUEDC1 promotes glycolytic metabolism reprogramming through the CUEDC1/CACNG4/PI3K axis to promote ER-positive breast cancer growth 6 samples shares glycolytic
- GSE249493 An atlas of small non-coding RNAs in Human Preimplantation Development [RNA-seq] 103 samples shares preimplantation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.