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NSUN2 promotes T-ALL cell growth as anRNA m5C methyltransferase

GSE276394 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/03/17 Platform GPL24676
Summary
NSUN2 (NOP2/Sun RNA methyltransferase 2), a 5-methylcytosine (m5C) RNA methyltransferase is highly expressed and plays a proto-oncoprotein role in various cancers. However, the role of NSUN2 in T-ALL remains unknown, we aim to investigate the role of NSUN2 in T-ALL and delineate its underlying mechanism. Then RNA-Seq data were generated with NSUN2-silenced and control (scrambled) Jurkat cells from 3 independent RNA extracts. The differentially expressed transcripts comparing NSUN2-silenced cells with control cells are displayed.
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Also filed as BioProject PRJNA1157203 and SRA study SRP531802. Searching any of these in the dataset finder brings you back here.

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