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Detect IGF1R function in postnatal bone marrow mesenchymal stem cell

GSE276419 Mus musculus Expression profiling by high throughput sequencing 11 samples 2024/09/11 GPL13112
Summary
1. IGF1R signaling pathway is highly enriched in P0.5 BMMSC compared to adult BMMSC; 2. Niche factors are highly expressed in PDGFRa+Sca1+ (PaS) cells. 3. Knockout IGF1R in Prx1+ BMMSC significantly impaired niche factors expression in P0.5 BMMSC.
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