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ChIP-Seq analysis for histone H3.3 in HL-60 cells after combined treatment with ATRA and palbociclib

GSE276456 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 9 samples Submitted 2025/08/04 Platform GPL24676
Summary
It was reported that the CDK4/6 inhibitor, palbociclib, can enhance ATRA-induced myeloid differentiation in HL-60 cells. Therefore, in this study, chromatin remodeling was precisely analyzed with a focus on histone H3.3 deposition.
Published in
Enlarged PML-nuclear bodies trigger conflicting cell cycle signal-mediated cytotoxicity in leukemia cells
Baba T, Kumamoto S, Moriguchi Y et al. · Cell death & disease 2025 · PMID 40753178 · doi:10.1038/s41419-025-07911-7
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Also filed as BioProject PRJNA1157412 and SRA study SRP530725. Searching any of these in the dataset finder brings you back here.

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