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RNA-seq profiles of HepG2 control cells and HepG2-HBx cells

GSE276530 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/07/02 Platform GPL24676
Summary
Hepatocellular carcinoma (HCC) is mainly associated with chronic hepatitis B virus infection. Hepatitis B virus X protein (HBx) is closely related to the occurrence of liver cancer. To explore the molecular mechanism by which HBx affects the occurrence of hepatocellular carcinoma, we established a stable HCC cell line HepG2-HBx expressing HBx and analyzed the transcriptome profile by RNA-seq.
Published in
Hepatitis B virus X protein (HBx)-mediated immune modulation and prognostic model development in hepatocellular carcinoma
Zhong J, Li Y, Liu Y et al. · PloS one 2025 · PMID 40577282 · doi:10.1371/journal.pone.0325363
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Also filed as BioProject PRJNA1157784 and SRA study SRP531046. Searching any of these in the dataset finder brings you back here.

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