Acetyl-CoA metabolism determines the partitioning of lipids between adipose tissue and skin
RNA-seq (gene expression) · mouse · 29 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 29 samples: 29 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276591_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1157878 and SRA study SRP531170. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 29 sample titles: 29 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7988637 PN1-male-WT
- GSM7988638 PN2-male-WT
- GSM7988639 PN3-male-KO
- GSM7988640 PN5-male-KO
- GSM7988641 PN6-fe-WT
- GSM7988642 PN7-fe-WT
- GSM7988643 PN8-fe-KO
- GSM7988644 PN9-fe-KO
- GSM7988645 PN10-fe-KO
- GSM8502681 PN1_WT_F_12d
- GSM8502682 PN2_KO_M_12d
- GSM8502683 PN3_WT_M_12d
- GSM8502684 PN4_KO_F_12d
- GSM8502685 PN5_KO_M_12d
- GSM8502686 PN6_WT_M_12d
- GSM8502687 PN7_WT_F_12d
- GSM8502688 PN8_KO_F_12d
- GSM8502689 PN9_WT_F_12d
- GSM8502690 PN10_KO_F_12d
- GSM8502691 PN11_WT_M_12d
- GSM8502692 PN12_KO_M_12d
- GSM8502693 PN13_WT_M_21d
- GSM8502694 PN14_KO_M_21d
- GSM8502695 PN15_WT_M_21d
- GSM8502696 PN16_KO_M_21d
- GSM8502697 PN17_WT_M_21d
- GSM8502698 PN18_KO_M_21d
- GSM8502699 PN19_WT_M_21d
- GSM8502700 PN20_KO_M_21d
- GSE241627 Single-cell lineage tracing uncovers unique skin adipose hierarchy and Sox9-mediated differentiation of adipocyte precursors 12 samples shares adipose, skin
- GSE76853 Acetyl-CoA metabolism by ACSS2 regulates neuronal histone acetylation and long-term memory [RNA-seq] 16 samples shares acetyl-coa
- GSE266543 Misaligned feeding uncouples daily rhythms within brown adipose tissue and between peripheral clocks 144 samples shares adipose
- GSE237737 Transcriptomic profiling across 20 CC-RIX genetic backgrounds with and without high-fat high-sugar (HFHS) diet, and with and without metformin [adipose] 705 samples shares adipose
- GSE267727 Transcriptome profiling of non-islet metabolic tissues in ~500 DO mouse liver, adipose, heart, and skeletal muscle tissue from mice fed high-fat, high-sugar diet [heart] 482 samples shares adipose
- GSE266569 Transcriptome profiling of non-islet metabolic tissues in ~500 DO mouse liver, adipose, heart, and skeletal muscle tissue from mice fed high-fat, high-sugar diet. [Liver] 481 samples shares adipose
- GSE266549 Transcriptome profiling of non-islet metabolic tissues in ~500 DO mouse liver, adipose, and skeletal muscle tissue from mice fed high-fat, high-sugar diet. [Adipose] 468 samples shares adipose
- GSE310044 Dietary sulfur amino acid restriction elicits a cold-like transcriptional response in inguinal but not epididymal white adipose tissue of male mice 110 samples shares adipose
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.