GEO series
Transcriptomic signatures of antibody mediated rejection in early biopsies with negative histology in HLA incompatible kidney transplantation [RNA-seq]
GSE276593
Homo sapiens
Expression profiling by high throughput sequencing
32 samples
2024/12/26
GPL24676
Summary
Presensitized patients with circulating donor-specific antibodies (DSA) prior to transplantation are at risk for antibody-mediated rejection (ABMR). Peritransplant desensitization mitigates but does not eliminate the alloimmune response. We examined the possibility that subthreshold ABMR activity undetected by histology could be operating in some early biopsies.
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Paper (PMID 39687512) ↗
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