GEO series
RNA sequencing reveals that Taar5 gene knockout in mice up-regulate the striatal expression of genes involved in neuronal connectivity and synaptogenesis
GSE276664
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2024/12/05
GPL28457
Summary
Our study revealed the slight but significant shifts in the striatal expression profile related to TAAR5 depletion. We have found, that TAAR5-KO mice are characterised by activation of transcription and post-transcriptional mRNA modification processes in striatum and suppression of the expression of genes involved in cell differentiation, especially in gliogenesis, and Ras signal transduction.
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Paper (PMID 39594659) ↗
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