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T cell exhastion is programmed by dynamic 3D genome reorganization

GSE276723 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 7 samples Submitted 2026/06/03 Platform GPL34290
Summary
CTCF is recognized for its role in facilitating long-range chromatin interactions and 3D genome organization. In CD8+ T cells responding to chronic infection, CTCF undergoes redistribution to activate the exhausted cytotoxic effector (Tex-eff) program while simultaneously utilizing its insulation function to regulate the fate of precursors to stem-like exhausted T (Tex-prec) cells.
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Also filed as BioProject PRJNA1158758. Searching any of these in the dataset finder brings you back here.

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