Cell-type specific translated mRNA expression in the denervated cervical cord after stroke.
RNA-seq (gene expression) · mouse · 63 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 63 samples: 21 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Scg2 drives corticospinal circuit reorganization with spinal premotor interneurons and astrocytes for motor recovery after stroke in miceNature communications · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277064_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1160309 and SRA study SRP532365. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 63 samples.
How we read this: 21 replicated groups read from 63 sample titles; they account for 63 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8513372 V2a, Control, rep1 V2a, Control,
- GSM8513373 V2a, Control, rep2 V2a, Control,
- GSM8513374 V2a, Control, rep3 V2a, Control,
- GSM8513375 V2a, Day 3, rep1 V2a, Day 3,
- GSM8513376 V2a, Day 3, rep2 V2a, Day 3,
- GSM8513377 V2a, Day 3, rep3 V2a, Day 3,
- GSM8513378 V2a, Day 7, rep1 V2a, Day 7,
- GSM8513379 V2a, Day 7, rep2 V2a, Day 7,
- GSM8513380 V2a, Day 7, rep3 V2a, Day 7,
- GSM8513381 V2a, Day 14, rep1 V2a, Day 14,
- GSM8513382 V2a, Day 14, rep2 V2a, Day 14,
- GSM8513383 V2a, Day 14, rep3 V2a, Day 14,
- GSM8513384 V2a, Day 28, rep1 V2a, Day 28,
- GSM8513385 V2a, Day 28, rep2 V2a, Day 28,
- GSM8513386 V2a, Day 28, rep3 V2a, Day 28,
- GSM8513387 Astrocyte, Control, rep1 Astrocyte, Control,
- GSM8513388 Astrocyte, Control, rep2 Astrocyte, Control,
- GSM8513389 Astrocyte, Control, rep3 Astrocyte, Control,
- GSM8513390 Astrocyte, Day 3, rep1 Astrocyte, Day 3,
- GSM8513391 Astrocyte, Day 3, rep2 Astrocyte, Day 3,
- GSM8513392 Astrocyte, Day 3, rep3 Astrocyte, Day 3,
- GSM8513393 Astrocyte, Day 7, rep1 Astrocyte, Day 7,
- GSM8513394 Astrocyte, Day 7, rep2 Astrocyte, Day 7,
- GSM8513395 Astrocyte, Day 7, rep3 Astrocyte, Day 7,
- GSM8513396 Astrocyte, Day 14, rep1 Astrocyte, Day 14,
- GSM8513397 Astrocyte, Day 14, rep2 Astrocyte, Day 14,
- GSM8513398 Astrocyte, Day 14, rep3 Astrocyte, Day 14,
- GSM8513399 Astrocyte, Day 28, rep1 Astrocyte, Day 28,
- GSM8513400 Astrocyte, Day 28, rep2 Astrocyte, Day 28,
- GSM8513401 Astrocyte, Day 28, rep3 Astrocyte, Day 28,
- GSM8513402 Microglia, Control, rep1 Microglia, Control,
- GSM8513403 Microglia, Control, rep2 Microglia, Control,
- GSM8513404 Microglia, Control, rep3 Microglia, Control,
- GSM8513405 Microglia, Day 3, rep1 Microglia, Day 3,
- GSM8513406 Microglia, Day 3, rep2 Microglia, Day 3,
- GSM8513407 Microglia, Day 3, rep3 Microglia, Day 3,
- GSM8513408 Microglia, Day 7, rep1 Microglia, Day 7,
- GSM8513409 Microglia, Day 7, rep2 Microglia, Day 7,
- GSM8513410 Microglia, Day 7, rep3 Microglia, Day 7,
- GSM8513411 Microglia, Day 14, rep1 Microglia, Day 14,
+ 23 more — browse all 63 samples with per-sample file links →
- GSE301254 Single-nucleus profiling reveals a core disease signature and cell-type-specific vulnerabilities in early Rett syndrome 32 samples shares cell-type, specific
- GSE205029 Single Cell Sequencing Data of Mouse Spinal Cord with Dorsal Column Lesion and Astrocyte-Specific Ryk conditional Knockout 16 samples shares specific, cord
- GSE348719 Longitudinal Machine Learning and snRNA-Seq Reveal Stroke-Specific Behavioral and Transcriptional Signatures 10 samples shares specific, stroke
- GSE331488 A global view of cell-type-specific temporal dynamics in mammalian aging [I] 771 samples shares cell-type, specific
- GSE331489 A global view of cell-type-specific temporal dynamics in mammalian aging [II] 725 samples shares cell-type, specific
- GSE305064 FOXP3 Expression Depends on Cell-Type Specific Cis-Regulatory Element and Transcription Factor Circuitry [mouse_Tconv_ChIP-seq] 15 samples shares cell-type, specific
- GSE272369 Cell-Type-Specific Epigenetic Priming of Gene Expression in Nucleus Accumbens by Cocaine 12 samples shares cell-type, specific
- GSE267938 Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement 256 samples shares specific
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.